THE VIAGRA RESEARCHING

Tuesday, March 24, 2009 6:20

A much more extensive study was begun. This time, 351 patients, between the ages of twenty-four and seventy, participated. Randomly, the men were assigned to take the pill at one of three doses (10, 25, or 50 mg) or a placebo. After twenty-eight days, almost 90 percent of the men taking the 50 mg pill reported a threefold improvement in the quality of their sex lives. They cited satisfaction with the frequency, hardness, and duration of their erections.

“The drug has given me back my life,” one man told Dr. Osterloh. It’s changed the way I think about myself. I’m a new man,” he said.

Viagra had a powerful effect on the men who tried it, and when the Phase II trial ended and the supply of the drug was stopped, there were a lot of complaints and protests from the test subjects. In fact, one test subject, who had developed ED years earlier, pleaded to be allowed to continue using the drug. Viagra, he said, had altered his life. In his ease, the researchers relented and gave it to him. He was, after all, almost ninety.

For Phase III, the trials were moved to the United States under the direction of Dr. Tom Lue, a noted San Francisco urologist. Now, unlike the highly successful European trials which had specifically excluded any man whose ED had a physiological basis, the American tests focused solely on men with physical problems. Subjects with atherosclerosis or a nerve-related problem like diabetes mellitus, were chosen. The results reinforced the power of Viagra. The European trials proved that it could help men whose ED was contributed to by anxiety or emotional problems. Now the American trials showed that ED related to physiological problems could also be overcome.

In the American study, 416 men with ED problems were randomly chosen to receive either a placebo or a 5, 25, 50, or 100 mg daily dose of Viagra over an eight-week period. Once again, when the study was ended a questionnaire was used to assess sexual satisfaction. More than 70percent can of the men answered that 50 mg of Viagra improved their i.. nous. More than 75 percent said that double that dosage imparted the desired effect.

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